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Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
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The sphingomyelin synthase 2 (SGMS2) protein plays a crucial role in plasma membrane sphingomyelin synthesis It catalyzes the reversible transfer of the phosphocholine moiety in sphingomyelin biosynthesis to form ceramide phosphocholine Sphingomyelin Synthase 2/SGMS2 Protein Human (HEK293 Fc) is the recombinant human-derived Sphingomyelin Synthase 2/SGMS2 protein expressed by HEK293 with N-mFc labeled tag
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Nomegestrol acetate is a selective progestogen and progesterone receptor agonist used in research as an analytical standard or reagent. Available as a 10 mM solution in DMSO (1 mL) and in solid form, it has confirmed identity and documentation for laboratory use. CAS: 58652-20-3; formula: C23H30O4; molar mass: 370.48 g·mol-1.
High purity (99.7%) suitable for analytical work.
Pre-diluted 10 mM solution in DMSO for convenience.
Also available as a solid for custom preparation.
Certificate of analysis and safety data available.
Appropriate for progesterone receptor assays and pharmacology studies.
Store per supplier instructions to maintain stability.
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JV-1-36 acetate is a growth hormone-releasing hormone (GHRH) antagonist that demonstrates antioxidant effects, inhibiting reactive oxygen species in A549 lung cancer cells and reducing cell viability in A549 and Hela cells. It is suitable for in vitro research on GHRH antagonists.
GHRH antagonist
Inhibits reactive oxygen species in A549 lung cancer cells
Reduces cell viability in A549 and Hela cells
Suitable for in vitro research on GHRH antagonists
Exerts antioxidant effects
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N-myristoyl-RKRTLRRL inhibits the binding of PKC substrates. It also inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with an IC50 of 5 μM and histone phosphorylation with an IC50 of 80 μM.
Inhibits binding of PKC substrates.
Inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation (IC50 of 5 μM).
Also inhibits histone phosphorylation (IC50 of 80 μM).
Appears as a white to off-white solid.
Sequence: {Myr}-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu.
Soluble in DMSO (50 mg/mL), requiring ultrasonic for dissolution.
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Selcopintide (Cpne7-DP) acetate is a synthetic peptide that corresponds to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. It highly reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP, and Nestin. Selcopintide acetate promotes dentin regeneration in dentinal defects of various degrees, and the regenerated hard tissue demonstrates the characteristics of true dentin.
Synthetic peptide corresponding to hCPNE7 protein fragment
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Vitamin D receptor (VDR) acts as a nuclear receptor for calcitriol the active form of vitamin D3 triggering cellular effects After vitamin D3 binding VDR translocates to the nucleus and forms a heterodimer with the retinoid X receptor (RXR) Vitamin D Receptor/VDR Protein Human (sf9 His) is the recombinant human-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-10 His labeled tag
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